Dissemination of antimicrobial resistance in Klebsiella spp. from urban aquatic environments: a multi-country genomic perspective
Our findings highlight significant regional disparities in CRKP prevalence and ARG dissemination across urban aquatic environments, with Nepal showing the highest prevalence, particularly in untreated rivers. China exhibited lower prevalence but distinct resistance gene profiles, while no CRKP was detected in Sri Lanka, underscoring the impact of environmental management and healthcare infrastructure on ARG spread.
Authors
- Xiaoyang Ju
- Yu Zhang (ORCID: https://orcid.org/0000-0003-4495-3447)
- Yuchen Wu (ORCID: https://orcid.org/0000-0002-7782-5188)
- Dev Raj Joshi (ORCID: https://orcid.org/0000-0003-4698-6322)
- Ruichao Li (ORCID: https://orcid.org/0000-0001-8333-9891)
- Chunzhen Wang
- Zelin Yan (ORCID: https://orcid.org/0009-0008-8984-2031)
- Tista Prasai Joshi (ORCID: https://orcid.org/0000-0003-4783-8452)
- Yan Li (ORCID: https://orcid.org/0000-0002-1567-9365)
- Yanyan Zhang (ORCID: https://orcid.org/0000-0002-2827-8042)
- Rong Zhang (ORCID: https://orcid.org/0000-0003-1188-0640)
- Jing Zhang (ORCID: https://orcid.org/0000-0003-2281-5297)
- Hanyu Wang (ORCID: https://orcid.org/0000-0002-6923-680X)
Institutions
- Ministry of Education (NZ)
- Tribhuvan University (NP)
- Chinese Academy of Sciences (CN)
- Research Center for Eco-Environmental Sciences (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- China Agricultural University (CN)
- Nepal Academy of Science and Technology (NP)
- Yangzhou University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1016/j.jare.2025.09.020
- Citations
- 1
- Primary Topic
- Pharmaceutical and Antibiotic Environmental Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.50