Impact of cardiometabolic conditions on the progression from mild cognitive impairment to dementia: A large cohort study
Type 2 diabetes, hypertension, and hyperlipidemia are associated with a high risk of developing all-cause dementia in participants already diagnosed with mild cognitive impairment (MCI). Type 2 diabetes was shown to pose a high risk for the progression from MCI to vascular dementia. Hyperlipidemia was associated with Alzheimer's disease progression in individuals with MCI.
Authors
- Ilya M. Nasrallah (ORCID: https://orcid.org/0000-0003-2346-7562)
- Christos A. Davatzikos (ORCID: https://orcid.org/0000-0002-1025-8561)
- Lu Li (ORCID: https://orcid.org/0000-0002-2891-6067)
- Junhao Wen
- S. Nagarajan
- Konrad Talbot (ORCID: https://orcid.org/0000-0003-4549-0835)
- Filippos Anagnostakis (ORCID: https://orcid.org/0000-0001-7374-8798)
- Michail Kokkorakis (ORCID: https://orcid.org/0000-0002-0027-5659)
- Christos Asvestis (ORCID: https://orcid.org/0009-0003-5565-030X)
- Ilias Papadimopoulos
- Yong Chen (ORCID: https://orcid.org/0000-0003-0835-0788)
Institutions
- University of the Sciences (US)
- University Medical Center Groningen (NL)
- National and Kapodistrian University of Athens (GR)
- Loma Linda University (US)
- University of the Arts (US)
- Artificial Intelligence in Medicine (Canada) (CA)
- University of Missouri–Kansas City (US)
- Columbia University (US)
- University of Pennsylvania (US)
- University of Bologna (IT)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/alz.70692
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47