Severe dengue hemorrhagic fever after TAK-003 dengue vaccination: A case report of a potential vaccine-associated adverse reaction
We report a severe dengue case that developed symptoms 5 days post-TAK-003 dengue vaccine administration. Whole-genome sequencing confirmed co-detection of all four dengue serotypes with high similarity to vaccine strains, especially DENV-2. This finding warrants further investigation into a potential association with vaccine adverse events.
Authors
- Artittaya Athipanyasilp
- Kamol Suwannakarn
- Pinyo Rattanaumpawan (ORCID: https://orcid.org/0000-0002-2964-6732)
- Ubonvan Jongwutiwes
- Navin Horthongkham (ORCID: https://orcid.org/0000-0001-9109-1259)
Institutions
- Siriraj Hospital (TH)
- Mahidol University (TH)
- Bangkok Hospital (TH)
- Mahidol Oxford Tropical Medicine Research Unit (TH)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-09-13
- DOI
- https://doi.org/10.1016/j.ijid.2025.108062
- Citations
- 4
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 7.51