Gas‑Forming Hepatic Metastases Due to Clostridium septicum Infection: A Rare Case Documented with Sequential CT Imaging

A rare case of hepatic gas-forming metastases secondary to <i>Clostridium septicum</i> infection is described. A 78-year-old woman was admitted with right lower quadrant abdominal pain and deterioration. Initial imaging revealed a right-sided colonic malignancy with hepatic metastases. Follow-up scans showed gas within metastases and minimal pneumoperitoneum, suggesting bowel perforation. However, blood cultures isolated <i>C. septicum</i>, supporting infected necrotic metastases as the source of free gas. <i>Teaching point:</i> This case emphasizes the importance of distinguishing infectious intratumoral gas from perforation in oncological patients and provides one of the few reports with sequential imaging of this process.

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Publication Details

Journal
Journal of the Belgian Society of Radiology
Published
2025-01-01
DOI
https://doi.org/10.5334/jbsr.4079
Primary Topic
Amoebic Infections and Treatments
Type
article
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article

Gas‑Forming Hepatic Metastases Due to Clostridium septicum Infection: A Rare Case Documented with Sequential CT Imaging

Nasroola Damry, Nguyễn Hoàng Định, Mattia's Loverde
Journal of the Belgian Society of Radiology
Amoebic Infections and Treatments
article

Gas‑Forming Hepatic Metastases Due to Clostridium septicum Infection: A Rare Case Documented with Sequential CT Imaging

Nasroola Damry, Nguyễn Hoàng Định, Mattia's Loverde
article en

Abstract

A rare case of hepatic gas-forming metastases secondary to <i>Clostridium septicum</i> infection is described. A 78-year-old woman was admitted with right lower quadrant abdominal pain and deterioration. Initial imaging revealed a right-sided colonic malignancy with hepatic metastases. Follow-up scans showed gas within metastases and minimal pneumoperitoneum, suggesting bowel perforation. However, blood cultures isolated <i>C. septicum</i>, supporting infected necrotic metastases as the source of free gas. <i>Teaching point:</i> This case emphasizes the importance of distinguishing infectious intratumoral gas from perforation in oncological patients and provides one of the few reports with sequential imaging of this process.

Journal of the Belgian Society of RadiologyVol. 109(1)
Centre Hospitalier Universitaire Brugmann (BE)
Openalex Percentile: Top 71%
Amoebic Infections and Treatments
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Gas‑Forming Hepatic Metastases Due to Clostridium septicum Infection: A Rare Case Documented with Sequential CT Imaging — Nasroola Damry, Nguyễn Hoàng Định, et al. · Journal of the Belgian Society of Radiology (2025) | TGRS Research Map | TGRS