Naringenin targets and inhibits Monoamine Oxidase A/B to bidirectionally regulate intestinal motility.
The results confirmed that NAR can regulate the activities of MAO-A/B in a threshold-dependent manner to achieve bidirectional regulation of intestinal motility.
Authors
- Tianshu Xu (ORCID: https://orcid.org/0009-0001-4198-0784)
- Yunzhi Qian (ORCID: https://orcid.org/0000-0002-4798-4700)
- Yujuan Wang (ORCID: https://orcid.org/0000-0003-2648-0850)
- Ling Fang (ORCID: https://orcid.org/0000-0003-2092-3681)
- Yige Zhang
- Qi Li
- Chao Xu (ORCID: https://orcid.org/0000-0001-8320-4698)
- Ting Tang (ORCID: https://orcid.org/0009-0001-8429-8224)
- Yi Chen (ORCID: https://orcid.org/0009-0003-5440-289X)
- Ong Shun Seng
Institutions
- University of North Carolina at Chapel Hill (US)
- Nanjing University of Chinese Medicine (CN)
- Nantong University (CN)
- Nanjing Traditional Chinese Medicine Hospital (CN)
- Nanjing Drum Tower Hospital (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Chemico-Biological Interactions
- Published
- 2025-09-12
- DOI
- https://doi.org/10.1016/j.cbi.2025.111742
- Citations
- 1
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.81