The effect of interfractional variation on delivered dose with ultrahypofractionated pencil beam scanning proton therapy for localized prostate cancer
Multivariate models incorporating bladder volume changes and CTV shifts accurately predict dosimetric deviations in PBS-SBRT. These findings highlight the need for adaptive strategies during PBS-SBRT to mitigate the impact of interfractional variations, optimize dose delivery precision, and reduce toxicity in high-risk patients.
Authors
- Keyur D Shah (ORCID: https://orcid.org/0000-0002-0886-655X)
- Vishal R. Dhere (ORCID: https://orcid.org/0000-0002-8364-7488)
- Jun Zhou (ORCID: https://orcid.org/0000-0002-6078-9424)
- Hania Al‐Hallaq (ORCID: https://orcid.org/0000-0003-4274-6524)
- Anees Dhabaan (ORCID: https://orcid.org/0000-0002-6426-2443)
- Sagar A. Patel (ORCID: https://orcid.org/0000-0001-5174-2096)
- Duncan Bohannon
- Chih‐Wei Chang (ORCID: https://orcid.org/0000-0002-3818-4381)
- Yi-Nan Wang (ORCID: https://orcid.org/0000-0001-7418-1519)
- Xiaofeng Yang (ORCID: https://orcid.org/0000-0001-9023-5855)
Institutions
- Emory University (US)
Publication Details
- Journal
- Journal of Applied Clinical Medical Physics
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/acm2.70223
- Citations
- 1
- Primary Topic
- Spectroscopy Techniques in Biomedical and Chemical Research
- Type
- article
- Field-Weighted Citation Impact
- 1.63