Higher PHQ-9 score levels and neutrophil-to-lymphocyte ratio are associated with increased risks of stroke, all-cause mortality, and MACE in NHANES 2005–2018
Our research indicates that elevated NLR levels and more severe depressive symptoms were associated with increased risk of stroke, all-cause mortality and MACE. In addition, NLR plays a mediation role in linking depressive symptoms to stroke, MACE, and all-cause mortality.
Authors
- Yang Han (ORCID: https://orcid.org/0000-0002-3105-6248)
- Zhaoyao Chen (ORCID: https://orcid.org/0000-0002-8441-5355)
- Yujun Cong (ORCID: https://orcid.org/0009-0007-6741-0468)
- Hui Jiang (ORCID: https://orcid.org/0000-0002-0277-9711)
- Minghua Wu (ORCID: https://orcid.org/0000-0002-6701-8825)
- Liu Hong-quan
- Aimei Zhang (ORCID: https://orcid.org/0000-0002-3571-3065)
- Yuan Zhu (ORCID: https://orcid.org/0000-0001-5871-4418)
- Xiaogang Tang
- Jingyi Chen (ORCID: https://orcid.org/0009-0007-0141-2241)
- Yan Liu (ORCID: https://orcid.org/0000-0001-7294-6661)
- Li Li (ORCID: https://orcid.org/0000-0003-4802-8689)
- Wenlei Li (ORCID: https://orcid.org/0000-0003-3960-6512)
- Junqi Liao
- Yunze Li (ORCID: https://orcid.org/0000-0001-9269-5644)
- Wei Peng (ORCID: https://orcid.org/0000-0002-0317-6939)
- Qing Zhu
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- BMC Psychiatry
- Published
- 2025-09-13
- DOI
- https://doi.org/10.1186/s12888-025-07198-0
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.58