Comparing the proteome profiling of plasma-derived extracellular vesicles in individuals with schizophrenia and healthy controls: a pilot study
Overall, even as our findings highlight the importance of medication use and duration of illness on EV protein levels, they suggest that the complement system may be involved in the etiopathology of SCZ. Although, the results of this pilot study need to be replicated in larger research, they may help elucidate the mechanisms involved in the pathophysiology of SCZ.
Authors
- Thorsten Müller (ORCID: https://orcid.org/0000-0002-0173-3412)
- Urs Heilbronner (ORCID: https://orcid.org/0000-0001-7135-762X)
- Mojtaba Oraki Kohshour (ORCID: https://orcid.org/0000-0002-1357-2636)
- Anton Eberharter
- Moritz J. Rossner (ORCID: https://orcid.org/0000-0002-0667-3420)
- Sergi Papiol (ORCID: https://orcid.org/0000-0001-9366-8728)
- Teresa K. Barth
- Andreas Klingl (ORCID: https://orcid.org/0000-0001-8414-8317)
- Thomas G. Schulze (ORCID: https://orcid.org/0000-0001-6624-2975)
- Monika Budde (ORCID: https://orcid.org/0000-0001-7301-9157)
- Florian J. Raabe (ORCID: https://orcid.org/0000-0001-8538-0783)
- Andrea Schmitt (ORCID: https://orcid.org/0000-0002-5426-4023)
- Peter Falkai (ORCID: https://orcid.org/0000-0002-0284-2290)
- Axel Imhof (ORCID: https://orcid.org/0000-0003-2993-8249)
- Chiara Huber
- Jennifer Grünert
- Monika Rübekeil
Institutions
- Federal Office for Radiation Protection (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Schizophrenia Research
- Published
- 2025-09-13
- DOI
- https://doi.org/10.1016/j.schres.2025.09.008
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- International Max Planck Research School for Environmental, Cellular and Molecular Microbiology
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung
- Ludwig-Maximilians-Universität München
- International Max Planck Research School for Advanced Methods in Process and Systems Engineering