Targeting CD161 inhibitory receptors enhances NK cell-mediated changes in synovial fibroblast function in rheumatoid arthritis

CD161 is a potential biomarker for RA. Targeted inhibition of CD161 in NK cells alleviates synovial inflammation in RA, highlighting its therapeutic potential.

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Publication Details

Journal
International Immunopharmacology
Published
2025-09-12
DOI
https://doi.org/10.1016/j.intimp.2025.115528
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.00
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article

Targeting CD161 inhibitory receptors enhances NK cell-mediated changes in synovial fibroblast function in rheumatoid arthritis

Tao You, Jia‐Le Song, Guangxue Gu, Jian Zhou et al.
International Immunopharmacology
Immune Cell Function and Interaction
article

Targeting CD161 inhibitory receptors enhances NK cell-mediated changes in synovial fibroblast function in rheumatoid arthritis

Tao You, Jia‐Le Song, Guangxue Gu, Jian Zhou, Hongwei Yu, Junqin Lu, Wei Zhou, Song Fu, Haoyu Zhao
article en

Abstract

CD161 is a potential biomarker for RA. Targeted inhibition of CD161 in NK cells alleviates synovial inflammation in RA, highlighting its therapeutic potential.

International ImmunopharmacologyVol. 165
University of Science and Technology of China (CN), Anhui Medical University (CN), The First People’s Hospital of Lianyungang (CN), 181st Hospital of Chinese People's Liberation Army (CN), First Affiliated Hospital of Anhui Medical University (CN), Second Affiliated Hospital of Anhui Medical University (CN)
Openalex Percentile: Top 74%
Immune Cell Function and Interaction
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