The impact of fine-tuning LLMs on the quality of automated therapy assessed by digital patients

The use of generative large language models (LLMs) in mental health applications is gaining traction, with some proposals even suggesting LLM-based automated therapists. In this study, we assess the impact of fine-tuning therapist LLMs to improve the quality of therapy sessions, addressing a critical question in LLM-based mental health research. Specifically, we demonstrate that fine-tuning with datasets focused on specific therapeutic techniques significantly enhances the performance of LLM therapists. To facilitate this assessment, we introduce a novel evaluation system based on digital patients, powered by LLMs, which engage in text-based therapy sessions and provide session evaluations through questionnaires designed for human patients. This method addresses the inadequacies of traditional text-similarity metrics, which are insufficient for assessing the quality of therapeutic interactions. This study centers on motivational interviewing (MI), a structured and goal-oriented therapeutic approach. However, our digital therapists and patients can be adapted to work in other forms of therapy. We believe that our digital therapists offer a standardized method for assessing automated therapists and showcasing the potential of LLMs in mental health care.

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Publication Details

Journal
npj Mental Health Research
Published
2025-09-13
DOI
https://doi.org/10.1038/s44184-025-00159-1
Citations
1
Primary Topic
Mental Health via Writing
Type
article
Field-Weighted Citation Impact
2.44
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article

The impact of fine-tuning LLMs on the quality of automated therapy assessed by digital patients

Doron Friedman, S. Yosef, Kfir Bar, Anat Brunstein Klomek et al.
1 citations
npj Mental Health Research
Mental Health via Writing
2.44
article

The impact of fine-tuning LLMs on the quality of automated therapy assessed by digital patients

Doron Friedman, S. Yosef, Kfir Bar, Anat Brunstein Klomek, Brian Cohen, ‪Moreah Zisquit‬‏
article en
1 citations

Abstract

The use of generative large language models (LLMs) in mental health applications is gaining traction, with some proposals even suggesting LLM-based automated therapists. In this study, we assess the impact of fine-tuning therapist LLMs to improve the quality of therapy sessions, addressing a critical question in LLM-based mental health research. Specifically, we demonstrate that fine-tuning with datasets focused on specific therapeutic techniques significantly enhances the performance of LLM therapists. To facilitate this assessment, we introduce a novel evaluation system based on digital patients, powered by LLMs, which engage in text-based therapy sessions and provide session evaluations through questionnaires designed for human patients. This method addresses the inadequacies of traditional text-similarity metrics, which are insufficient for assessing the quality of therapeutic interactions. This study centers on motivational interviewing (MI), a structured and goal-oriented therapeutic approach. However, our digital therapists and patients can be adapted to work in other forms of therapy. We believe that our digital therapists offer a standardized method for assessing automated therapists and showcasing the potential of LLMs in mental health care.

npj Mental Health ResearchVol. 4(1)
Reichman University (IL)
Openalex Percentile: Top 10%
Mental Health via Writing
2.44
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