A comprehensive single-cell atlas of three centenarian cohorts unveils unique natural killer cell signatures and enhanced mutual interactions among peripheral immune cells
This study was funded by the Sanya Science and Technology Innovation Special Project (No. 2022KJCX02), National Natural Science Foundation of China (No. 32141005, 82270769), Specific Research Fund of the Innovation Platform for Academicians of Hainan Province, and National Key Research and Development Program of China (Nos. 2022YFC3602900, 2022YFC3602902, 2022YFC3602903).
Authors
- Qingtao Zhang (ORCID: https://orcid.org/0000-0002-6972-8265)
- Xiangmei Chen (ORCID: https://orcid.org/0009-0004-5082-3387)
- Mingda Duan
- Zehao Zhang (ORCID: https://orcid.org/0000-0002-7568-5775)
- Zeyu Qu
- Yizhi Chen
- Zhifeng Gu (ORCID: https://orcid.org/0000-0002-3275-0733)
- Bin Wang (ORCID: https://orcid.org/0000-0002-9945-1818)
- Hao Li (ORCID: https://orcid.org/0000-0002-9773-8313)
- Min Zhang (ORCID: https://orcid.org/0000-0002-9169-1024)
- Jie Zhang (ORCID: https://orcid.org/0000-0002-2178-0558)
- Xinye Jin (ORCID: https://orcid.org/0000-0002-5167-6524)
- Hongyan Hu
- Ding Sun
- Qing Ouyang
- Qing Luo (ORCID: https://orcid.org/0009-0006-9919-116X)
Institutions
- Nantong University (CN)
- Chinese PLA General Hospital (CN)
- Affiliated Hospital of Nantong University (CN)
- Hainan General Hospital (CN)
- Hainan 301 Hospital (CN)
- Hainan 301 Hospital (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- EBioMedicine
- Published
- 2025-09-13
- DOI
- https://doi.org/10.1016/j.ebiom.2025.105922
- Citations
- 3
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.53