Angular Sign of Henle Fiber Layer Hyperreflectivity (ASHH) in Cancer-Associated Retinopathy
CAR eyes in our series who presented with ASHH lesions demonstrated a rapidly progressive course, culminating in severe EZ loss and outer retinal atrophy with characteristic hyperreflective granularity on OCT. The presence of ASHH lesions may serve as an early OCT biomarker of photoreceptor toxicity in paraneoplastic retinopathy and is a poor prognostic factor.
Authors
- Alessandro Feo (ORCID: https://orcid.org/0009-0005-2999-6782)
- Edmund Yik Kong Tsui (ORCID: https://orcid.org/0000-0001-7532-9191)
- Marko M. Popovic (ORCID: https://orcid.org/0000-0002-0370-5968)
Institutions
- Humanitas University (IT)
Publication Details
- Journal
- Ocular Immunology and Inflammation
- Published
- 2025-09-12
- DOI
- https://doi.org/10.1080/09273948.2025.2552925
- Citations
- 1
- Primary Topic
- Drug-Induced Ocular Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 1.71