Trends in first‐line monotherapy and combination therapy for hypertension in UK primary care

First-line antihypertensive combination therapy remains exceedingly rare in the UK in accordance with National Institute for Health and Care Excellence guidelines, but in contrast to other international recommendations. Treatment persistence was lower on first-line combination therapy than monotherapy.

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Publication Details

Journal
British Journal of Clinical Pharmacology
Published
2025-09-13
DOI
https://doi.org/10.1002/bcp.70271
Primary Topic
Blood Pressure and Hypertension Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Trends in first‐line monotherapy and combination therapy for hypertension in UK primary care

James M. Brophy, Christel Renoux, Robert W. Platt, Kyle Johnson et al.
British Journal of Clinical Pharmacology
Blood Pressure and Hypertension Studies
article

Trends in first‐line monotherapy and combination therapy for hypertension in UK primary care

James M. Brophy, Christel Renoux, Robert W. Platt, Kyle Johnson, Sarah Beradid
article en

Abstract

First-line antihypertensive combination therapy remains exceedingly rare in the UK in accordance with National Institute for Health and Care Excellence guidelines, but in contrast to other international recommendations. Treatment persistence was lower on first-line combination therapy than monotherapy.

British Journal of Clinical PharmacologyVol. 92(2)
Jewish General Hospital (CA), McGill University (CA)
Openalex Percentile: Top 62%
Blood Pressure and Hypertension Studies
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