Radiation therapy for amyloid‐producing odontogenic tumor in a cat: a case report

Amyloid-producing odontogenic tumor (APOT) is a rare odontogenic neoplasm in cats, characterized by amyloid deposition within the tumor. Surgical resection is commonly recommended, but in cases where complete excision is difficult, radiation therapy may be considered as an alternative treatment. In this case report, a 10-year-old male neutered domestic cat with an APOT of the maxilla was treated with radiation therapy and showed favorable outcomes. The treatment protocol involved a total dose of 42 Gy (Gray) administered over six sessions, with good tumor control, and minimal side effects observed over a 481-day follow-up period. This case suggests that radiation therapy can be an effective treatment option for APOT, particularly in cases where surgical excision is not feasible.

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Publication Details

Journal
Australian Veterinary Journal
Published
2025-09-13
DOI
https://doi.org/10.1111/avj.70021
Primary Topic
Oral and Maxillofacial Pathology
Type
article
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article

Radiation therapy for amyloid‐producing odontogenic tumor in a cat: a case report

Akihiro Uno, Takashi Mori
Australian Veterinary Journal
Oral and Maxillofacial Pathology
article

Radiation therapy for amyloid‐producing odontogenic tumor in a cat: a case report

Akihiro Uno, Takashi Mori
article en

Abstract

Amyloid-producing odontogenic tumor (APOT) is a rare odontogenic neoplasm in cats, characterized by amyloid deposition within the tumor. Surgical resection is commonly recommended, but in cases where complete excision is difficult, radiation therapy may be considered as an alternative treatment. In this case report, a 10-year-old male neutered domestic cat with an APOT of the maxilla was treated with radiation therapy and showed favorable outcomes. The treatment protocol involved a total dose of 42 Gy (Gray) administered over six sessions, with good tumor control, and minimal side effects observed over a 481-day follow-up period. This case suggests that radiation therapy can be an effective treatment option for APOT, particularly in cases where surgical excision is not feasible.

Australian Veterinary JournalVol. 104(1-2)
Gifu University of Medical Science (JP), Gifu University (JP)
Openalex Percentile: Top 66%
Oral and Maxillofacial Pathology
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