Effect of aspirin on maternal hemodynamics in <scp>Chinese</scp> women at high risk for preterm pre‐eclampsia: longitudinal study

This study highlights the significant differences in maternal hemodynamic adaptation during pregnancy between Chinese women at high risk and those at low risk for preterm PE. Compared with low-risk women, high-risk women exhibited increased MAP and SVR, along with reduced SV and CO as early as the first trimester, and these alterations persisted throughout gestation. Notably, aspirin prophylaxis showed a limited effect on improving maternal hemodynamics in women at high risk for preterm PE, highlighting the need for alternative strategies to address the hemodynamic maladaptation in high-risk women. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

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Publication Details

Journal
Ultrasound in Obstetrics and Gynecology
Published
2025-09-12
DOI
https://doi.org/10.1002/uog.70027
Primary Topic
Pregnancy and preeclampsia studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Effect of aspirin on maternal hemodynamics in Chinese women at high risk for preterm pre‐eclampsia: longitudinal study

Xinyu Xu, Liona C. Poon, X. Wang, A. P. W. Lee et al.
Ultrasound in Obstetrics and Gynecology
Pregnancy and preeclampsia studies
article

Effect of aspirin on maternal hemodynamics in Chinese women at high risk for preterm pre‐eclampsia: longitudinal study

Xinyu Xu, Liona C. Poon, X. Wang, A. P. W. Lee, Daljit Singh Sahota, So Ling Lau, Ian Chi Kei Wong, Yue Chen, Jing Lin, Qiushi Zhang, Jin Liu, Fengguang Liu
article en

Abstract

This study highlights the significant differences in maternal hemodynamic adaptation during pregnancy between Chinese women at high risk and those at low risk for preterm PE. Compared with low-risk women, high-risk women exhibited increased MAP and SVR, along with reduced SV and CO as early as the first trimester, and these alterations persisted throughout gestation. Notably, aspirin prophylaxis showed a limited effect on improving maternal hemodynamics in women at high risk for preterm PE, highlighting the need for alternative strategies to address the hemodynamic maladaptation in high-risk women. © 2025 The Author(s). Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

Ultrasound in Obstetrics and GynecologyVol. 66(5)
North Sichuan Medical University (CN), Chinese University of Hong Kong (HK), Prince of Wales Hospital (CN), Chinese University of Hong Kong, Shenzhen (CN), Fuzhou Maternity and Child Health Care Hospital (CN)
Chinese University of Hong Kong
Openalex Percentile: Top 70%
Pregnancy and preeclampsia studies
DOIOpen Access PDFOpenAlex
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Effect of aspirin on maternal hemodynamics in <scp>Chinese</scp> women at high risk for preterm pre‐eclampsia: longitudinal study — Xinyu Xu, Liona C. Poon, et al. · Ultrasound in Obstetrics and Gynecology (2025) | TGRS Research Map | TGRS