Decidual Cells Induce Release of Free and Exosome‐Bound Interferon Epsilon From Vaginal Epithelial Cells

Mucosal immune defense mediated by IFNε may be an innate response by VECs under OS. This was further evidenced by an overall increase in IFNε due to both physiologic and pathologic impact of decidua on VECs. IFNε may indicate a stress response by VECs or paracrine crosstalk between gestational tissues.

Authors

Emmanuel Amabebe (ORCID: https://orcid.org/0000-0002-3924-5270)
Brandie DePaoli Taylor (ORCID: https://orcid.org/0000-0002-8234-1815)
Lauren Richardson (ORCID: https://orcid.org/0000-0001-8392-2833)
Awanit Kumar
Ramkumar Menon

Institutions

Aurora Health Care (US)
The University of Texas Medical Branch at Galveston (US)

Publication Details

Journal: American Journal of Reproductive Immunology
Published: 2025-09-01
DOI: https://doi.org/10.1111/aji.70129
Citations: 1
Primary Topic: Reproductive System and Pregnancy
Type: article
Field-Weighted Citation Impact: 0.80

Funders

University of Texas Medical Branch
National Institutes of Health
National Institute of Allergy and Infectious Diseases

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article

Decidual Cells Induce Release of Free and Exosome‐Bound Interferon Epsilon From Vaginal Epithelial Cells

Emmanuel Amabebe, Brandie DePaoli Taylor, Lauren Richardson, Awanit Kumar et al.

Sep 1, 2025

1 citations

American Journal of Reproductive Immunology

Reproductive System and Pregnancy

0.80

article

Decidual Cells Induce Release of Free and Exosome‐Bound Interferon Epsilon From Vaginal Epithelial Cells

Emmanuel Amabebe, Brandie DePaoli Taylor, Lauren Richardson, Awanit Kumar, Ramkumar Menon

September 1, 2025article en

1 citations

Abstract

Mucosal immune defense mediated by IFNε may be an innate response by VECs under OS. This was further evidenced by an overall increase in IFNε due to both physiologic and pathologic impact of decidua on VECs. IFNε may indicate a stress response by VECs or paracrine crosstalk between gestational tissues.

American Journal of Reproductive ImmunologyVol. 94(3)

Aurora Health Care (US), The University of Texas Medical Branch at Galveston (US)

University of Texas Medical Branch, National Institutes of Health, National Institute of Allergy and Infectious Diseases

Openalex Percentile: Top 24%

Reproductive System and Pregnancy

0.80

DOI Open Access PDF OpenAlex

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Decidual Cells Induce Release of Free and Exosome‐Bound Interferon Epsilon From Vaginal Epithelial Cells — Emmanuel Amabebe, Brandie DePaoli Taylor, et al. · American Journal of Reproductive Immunology (2025) | TGRS Research Map | TGRS