Association between inflammatory score, coagulopathy, and hemorrhagic progression in patients with traumatic intraparenchymal hemorrhage: an exploratory study with interaction and mediation models
The inflammatory score was significantly associated with HPC, and this relationship was partially mediated by coagulopathy, with a potential synergistic interaction observed. The hybrid model improved HPC risk prediction.
Authors
- Zezheng Zheng
- Yinan Zhou (ORCID: https://orcid.org/0000-0003-1922-7750)
- Kuang Zheng
- Can Tang
- Haoqi Ni
- Peng Zhang (ORCID: https://orcid.org/0000-0003-0215-3572)
- Weizhong Zhang (ORCID: https://orcid.org/0000-0002-6515-5500)
- Zhiyuan Yan (ORCID: https://orcid.org/0000-0003-2286-2771)
- Yu Chen (ORCID: https://orcid.org/0009-0008-7166-2665)
- Zequn Li (ORCID: https://orcid.org/0000-0002-1601-7304)
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Northern Jiangsu People's Hospital (CN)
Publication Details
- Journal
- Journal of neurosurgery
- Published
- 2025-09-12
- DOI
- https://doi.org/10.3171/2025.5.jns25281
- Primary Topic
- Neurosurgical Procedures and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00