Cryptosporidium parvum protease INS6 plays an important role in parasite proliferation and pathogenicity
These results indicate that INS6 protein is involved in C. parvum proliferation and plays a critical role in modulating the pathogenicity of this zoonotic parasite. Deletion of this gene affects the invasion efficiency and pathogenicity of the parasite.
Authors
- Yaqiong Guo (ORCID: https://orcid.org/0000-0001-9958-1295)
- Yaoyu Feng (ORCID: https://orcid.org/0000-0002-8380-1246)
- Zuwei Yang
- Fuxian Yang
- Songrong Zeng
- Wei He (ORCID: https://orcid.org/0009-0004-3424-5783)
- Na Li (ORCID: https://orcid.org/0000-0003-0114-4877)
- Jing Wang (ORCID: https://orcid.org/0000-0002-4688-2403)
- Lihua Xiao (ORCID: https://orcid.org/0000-0001-8532-2727)
- Rui Xu (ORCID: https://orcid.org/0000-0001-8720-8979)
Institutions
- South China Agricultural University (CN)
- Shaoguan University (CN)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-09-12
- DOI
- https://doi.org/10.1371/journal.pntd.0013532
- Primary Topic
- Parasitic Infections and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00