Diverse short tandem repeat sequences influence gene regulation in human populations
Our findings underscore the previously unrecognized role of STR sequence variability in modulating gene expression and contributing to human phenotypic diversity.
Authors
- Giovanna Pellecchia (ORCID: https://orcid.org/0000-0003-4747-3473)
- Aleksandra Mitina (ORCID: https://orcid.org/0009-0005-3621-0549)
- Ryan K. C. Yuen (ORCID: https://orcid.org/0000-0001-7273-4968)
- Stephen W. Scherer (ORCID: https://orcid.org/0000-0002-8326-1999)
- Brett Trost (ORCID: https://orcid.org/0000-0003-4863-7273)
- Worrawat Engchuan (ORCID: https://orcid.org/0000-0001-6138-1925)
Institutions
- University of Toronto (CA)
- Hospital for Sick Children (CA)
- SickKids Foundation (CA)
Publication Details
- Journal
- Genome biology
- Published
- 2025-09-12
- DOI
- https://doi.org/10.1186/s13059-025-03754-9
- Primary Topic
- Genetic Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canadian Institutes of Health Research