CYP2C19 Polymorphism and Clopidogrel Efficacy in Long-Term Outcomes of Large-Artery Atherosclerotic Stroke
In patients with LAA stroke, CYP2C19 PM/IMs had a significantly higher long-term recurrence rate of ischemic events than extensive metabolizers.
Authors
- Masafumi Ihara (ORCID: https://orcid.org/0000-0002-7102-4048)
- Yorito Hattori (ORCID: https://orcid.org/0000-0002-1495-4433)
- Kunihiro Nishimura (ORCID: https://orcid.org/0000-0002-0639-0949)
- Soshiro Ogata (ORCID: https://orcid.org/0000-0002-0100-376X)
- Hiroyuki Ishiyama (ORCID: https://orcid.org/0000-0003-0071-7338)
- Kenji Ninomiya (ORCID: https://orcid.org/0000-0003-1485-4675)
- Soichiro Abe (ORCID: https://orcid.org/0000-0001-9528-8702)
- Yuriko Nakaoku (ORCID: https://orcid.org/0000-0002-3100-574X)
- Takeshi Yoshimoto (ORCID: https://orcid.org/0000-0003-3178-8171)
Institutions
- National Cerebral and Cardiovascular Center (JP)
- University of Tsukuba Hospital (JP)
- Shimadzu (Japan) (JP)
Publication Details
- Journal
- JACC Asia
- Published
- 2025-09-13
- DOI
- https://doi.org/10.1016/j.jacasi.2025.07.020
- Citations
- 4
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 5.55