Evaluation of the Xpert MTB/XDR test for detection of isoniazid, fluoroquinolones, and second-line injectable drugs resistance to Mycobacterium tuberculosis—Anhui Province, China

The Xpert MTB/XDR has high sensitivity and specificity in drug-resistant tuberculosis patients, making it better suited to meet the needs of rapid, sensitive, and accurate detection for drug-resistant tuberculosis in resource-limited settings, and serving as a critical tool for achieving personalized treatment and TB control.

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Publication Details

Journal
PLoS ONE
Published
2025-09-12
DOI
https://doi.org/10.1371/journal.pone.0331264
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of the Xpert MTB/XDR test for detection of isoniazid, fluoroquinolones, and second-line injectable drugs resistance to Mycobacterium tuberculosis—Anhui Province, China

Bin Zhao, Xundi Bao, Zhou Liu, 崇匡 佐藤 et al.
PLoS ONE
Tuberculosis Research and Epidemiology
article

Evaluation of the Xpert MTB/XDR test for detection of isoniazid, fluoroquinolones, and second-line injectable drugs resistance to Mycobacterium tuberculosis—Anhui Province, China

Bin Zhao, Xundi Bao, Zhou Liu, 崇匡 佐藤, Xichao Ou, Fangjin Bao, Yanlin Zhao, Ruida Xing, Hui Xia, Yue Li, Dongfang Xu, Ruiqing Zhang
article en

Abstract

The Xpert MTB/XDR has high sensitivity and specificity in drug-resistant tuberculosis patients, making it better suited to meet the needs of rapid, sensitive, and accurate detection for drug-resistant tuberculosis in resource-limited settings, and serving as a critical tool for achieving personalized treatment and TB control.

PLoS ONEVol. 20(9)
Chinese Center For Disease Control and Prevention (CN), Anhui Provincial Center for Disease Control and Prevention (CN), National Institute for Communicable Disease Control and Prevention (CN), Beijing Center for Disease Prevention and Control (CN), Xi'an Chest Hospital (CN)
Openalex Percentile: Top 71%
Tuberculosis Research and Epidemiology
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