Tramadol (with or without acetaminophen) efficacy and harm
Tramadol with or without acetaminophen did not differ significantly from other opioids, and was less effective and more poorly tolerated than NSAIDs. Short study duration, small sample size, extensive patient exclusion, and inconsistency in outcome reporting limit the scientific validity of conclusions.
Authors
- Gavin S. Chu (ORCID: https://orcid.org/0000-0002-5952-8374)
- Ken Bassett
- Jessica Otte (ORCID: https://orcid.org/0009-0000-7598-7354)
- Benji Heran
Institutions
- University of British Columbia Hospital (CA)
- Media Working Group (US)
- Io Therapeutics (United States) (US)
Publication Details
- Journal
- Canadian Family Physician
- Published
- 2025-09-01
- DOI
- https://doi.org/10.46747/cfp.7109574
- Primary Topic
- Veterinary Pharmacology and Anesthesia
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of British Columbia