Improved time-to-detection with the new formulation of BD BACTEC Plus Aerobic/F Culture Vials: a real-world evidence study

Faster detection of infectious organisms can help improve patient prognosis. Recently, the formulation of aerobic culture vial media was modified for blood culture on the BD BACTEC instrument. The work presented here provides compelling evidence that the new aerobic media formulation improves time-to-detection for bloodstream infections. This has the potential to impact the healthcare treatment of millions of patients each year without requiring changes in clinical workflow. Faster time to detection can lead to faster organism identification and antimicrobial susceptibility testing (when appropriate). This report provides a comprehensive comparison of the novel media formulation with the predicate formulation for detecting multiple organism genera in both analytical and prospective clinical studies.

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Publication Details

Journal
Microbiology Spectrum
Published
2025-09-12
DOI
https://doi.org/10.1128/spectrum.01969-25
Primary Topic
Bacterial Identification and Susceptibility Testing
Type
article
Field-Weighted Citation Impact
0.00
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article

Improved time-to-detection with the new formulation of BD BACTEC Plus Aerobic/F Culture Vials: a real-world evidence study

Valentin Parvu, Kayla Van Benten, Mondraya F. Howard, Chris Massey et al.
Microbiology Spectrum
Bacterial Identification and Susceptibility Testing
article

Improved time-to-detection with the new formulation of BD BACTEC Plus Aerobic/F Culture Vials: a real-world evidence study

Valentin Parvu, Kayla Van Benten, Mondraya F. Howard, Chris Massey, Stephanie Frey
article en

Abstract

Faster detection of infectious organisms can help improve patient prognosis. Recently, the formulation of aerobic culture vial media was modified for blood culture on the BD BACTEC instrument. The work presented here provides compelling evidence that the new aerobic media formulation improves time-to-detection for bloodstream infections. This has the potential to impact the healthcare treatment of millions of patients each year without requiring changes in clinical workflow. Faster time to detection can lead to faster organism identification and antimicrobial susceptibility testing (when appropriate). This report provides a comprehensive comparison of the novel media formulation with the predicate formulation for detecting multiple organism genera in both analytical and prospective clinical studies.

Microbiology SpectrumVol. 13(10)
Becton Dickinson (United States) (US), Lancaster General Hospital (US)
Openalex Percentile: Top 73%
Bacterial Identification and Susceptibility Testing
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