Retinoic Acid Inhibition Alters Intestinal Composition in Zebrafish: A Non‐genetic Model to Study Hirschsprung Disease?
These findings highlight RA's pivotal role in maintaining intestinal structure and immune homeostasis, while further supporting the importance of considering both neuronal and non-neuronal cell populations in HSCR research.
Authors
- Naomi Kakiailatu (ORCID: https://orcid.org/0009-0007-5513-1496)
- Joke Zink
- Eric Bindels
- Emma de Pater (ORCID: https://orcid.org/0000-0002-7195-6769)
- Maria M. Alves (ORCID: https://orcid.org/0000-0003-0083-5318)
- Veerle Melotte (ORCID: https://orcid.org/0000-0002-9459-123X)
- Laura E. Kuil (ORCID: https://orcid.org/0000-0003-3330-1371)
- Wei Zhang (ORCID: https://orcid.org/0000-0002-0519-3935)
- Michael Vermeulen (ORCID: https://orcid.org/0000-0002-5854-9376)
Institutions
- Maastricht University Medical Centre (NL)
- Erasmus MC (NL)
- Maastricht University (NL)
- Erasmus MC - Sophia Children’s Hospital (NL)
- Maastro Clinic (NL)
Publication Details
- Journal
- Neurogastroenterology & Motility
- Published
- 2025-09-12
- DOI
- https://doi.org/10.1111/nmo.70155
- Primary Topic
- Congenital gastrointestinal and neural anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00