An Adolescent With a Granular Cell Bronchogenic Tumor: A Rare Case Report and Review of the Literature

Primary pulmonary tumors are rare in pediatric patients, and benign types are more frequently observed than malignant ones. Granular cell tumors (GCTs), of neuroectodermal origin, are uncommon in the lungs and especially rare in children. We report a case of a 16-year-old female with persistent respiratory symptoms initially diagnosed as asthma, who was ultimately found to have a bronchial granular cell tumor. The diagnosis was confirmed histopathologically, and the lesion was removed via rigid bronchoscopy. We also provide a review of the literature focusing on pediatric pulmonary GCTs. Granular cell tumors should be considered in the differential diagnosis of adolescents with persistent respiratory symptoms unresponsive to medical therapy. Early imaging and bronchoscopy can assist in timely diagnosis and lung-sparing treatment.

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Publication Details

Journal
Clinical Medicine Insights Pediatrics
Published
2025-09-01
DOI
https://doi.org/10.1177/11795565251366784
Primary Topic
Tumors and Oncological Cases
Type
article
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article

An Adolescent With a Granular Cell Bronchogenic Tumor: A Rare Case Report and Review of the Literature

Didar Ağca Cengiz, İrem Hicran Özbudak, Abdurrahman Erdem Başaran, Ayşen Bingöl et al.
Clinical Medicine Insights Pediatrics
Tumors and Oncological Cases
article

An Adolescent With a Granular Cell Bronchogenic Tumor: A Rare Case Report and Review of the Literature

Didar Ağca Cengiz, İrem Hicran Özbudak, Abdurrahman Erdem Başaran, Ayşen Bingöl, Irmak Tanal Şambel, Betül Bankoğlu Parlak
article en

Abstract

Primary pulmonary tumors are rare in pediatric patients, and benign types are more frequently observed than malignant ones. Granular cell tumors (GCTs), of neuroectodermal origin, are uncommon in the lungs and especially rare in children. We report a case of a 16-year-old female with persistent respiratory symptoms initially diagnosed as asthma, who was ultimately found to have a bronchial granular cell tumor. The diagnosis was confirmed histopathologically, and the lesion was removed via rigid bronchoscopy. We also provide a review of the literature focusing on pediatric pulmonary GCTs. Granular cell tumors should be considered in the differential diagnosis of adolescents with persistent respiratory symptoms unresponsive to medical therapy. Early imaging and bronchoscopy can assist in timely diagnosis and lung-sparing treatment.

Clinical Medicine Insights PediatricsVol. 19
Akdeniz University (TR)
Openalex Percentile: Top 65%
Tumors and Oncological Cases
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An Adolescent With a Granular Cell Bronchogenic Tumor: A Rare Case Report and Review of the Literature — Didar Ağca Cengiz, İrem Hicran Özbudak, et al. · Clinical Medicine Insights Pediatrics (2025) | TGRS Research Map | TGRS