Childhood Loneliness and Cognitive Decline and Dementia Risk in Middle-Aged and Older Adults
In this cohort study, childhood loneliness was associated with cognitive decline and dementia risk in middle and later adulthood, even in the absence of adult loneliness. Early interventions aimed at reducing childhood loneliness may help promote lifelong cognitive health and reducing dementia risk.
Authors
- Lixin Tao (ORCID: https://orcid.org/0000-0002-2135-046X)
- Xiaoyu Zhao (ORCID: https://orcid.org/0000-0001-8353-3109)
- Xiuhua Guo (ORCID: https://orcid.org/0000-0001-6657-6940)
- Zhiyuan Wu (ORCID: https://orcid.org/0000-0001-5694-2441)
- Yixing Tian (ORCID: https://orcid.org/0009-0000-4717-7784)
- Hui Chen (ORCID: https://orcid.org/0000-0002-1560-8540)
- Xia Li (ORCID: https://orcid.org/0000-0003-1890-5548)
- Chen Sheng (ORCID: https://orcid.org/0000-0002-0192-3830)
- Haibin Li (ORCID: https://orcid.org/0000-0002-6932-982X)
- Jinqi Wang (ORCID: https://orcid.org/0000-0002-4801-8408)
- Danyang Jiao
Institutions
- Boston University (US)
- Edith Cowan University (AU)
- Harvard University (US)
- Capital Medical University (CN)
- La Trobe University (AU)
- Second Affiliated Hospital of Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-09-12
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.31493
- Citations
- 6
- Primary Topic
- Health disparities and outcomes
- Type
- article
- Field-Weighted Citation Impact
- 13.00