Ex vivo human brain volumetry: Validation of MRI measurements

SynthSeg accurately determined the brain volume in ex vivo, in situ T<sub>1</sub>-weighted MRI scans. The results suggested that given the contrast similarity between the ex vivo and in vivo sequences, the brain volumes of clinical studies are most probably sufficiently accurate, with some degree of underestimation depending on the sequence used.

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Publication Details

Journal
Magnetic Resonance in Medicine
Published
2025-09-12
DOI
https://doi.org/10.1002/mrm.70083
Primary Topic
Advanced MRI Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

Ex vivo human brain volumetry: Validation of MRI measurements

Josefina Maranzano, Anna Nayouf, Éve‐Marie Frigon, Mahsa Dadar et al.
Magnetic Resonance in Medicine
Advanced MRI Techniques and Applications
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Ex vivo human brain volumetry: Validation of MRI measurements

Josefina Maranzano, Anna Nayouf, Éve‐Marie Frigon, Mahsa Dadar, Liana Guerra Sanches, Denis Boire, Walter Adame‐Gonzalez, Amy Gérin‐Lajoie
article en

Abstract

SynthSeg accurately determined the brain volume in ex vivo, in situ T<sub>1</sub>-weighted MRI scans. The results suggested that given the contrast similarity between the ex vivo and in vivo sequences, the brain volumes of clinical studies are most probably sufficiently accurate, with some degree of underestimation depending on the sequence used.

Magnetic Resonance in MedicineVol. 95(2)
Montreal Neurological Institute and Hospital (CA), Douglas Mental Health University Institute (CA), McGill University (CA), Université du Québec à Trois-Rivières (CA)
Openalex Percentile: Top 66%
Advanced MRI Techniques and Applications
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