Frozen section histopathology and preanalytical factors affecting nucleic acid integrity in biobanked fresh-frozen human cancer tissues
This study confirmed that nucleic acid integrity can be maintained even during long-term storage of FFT and demonstrated that histologic features are closely related to RNA quality. This study would contribute to the establishment of quality assessment and management standards for biobank FFT samples.
Authors
- Yoonjin Kwak (ORCID: https://orcid.org/0000-0001-5314-2465)
- Jaewon Kang (ORCID: https://orcid.org/0000-0001-5602-2856)
- S.H. Kim
- Hye Seung Lee (ORCID: https://orcid.org/0000-0003-4157-0862)
- Bo‐Yeon Kim (ORCID: https://orcid.org/0000-0002-3658-2351)
Institutions
- Seoul National University (KR)
- Cancer Research Institute (US)
- Seoul National University Hospital (KR)
Publication Details
- Journal
- Journal of Pathology and Translational Medicine
- Published
- 2025-09-12
- DOI
- https://doi.org/10.4132/jptm.2025.07.22
- Citations
- 1
- Primary Topic
- Molecular Biology Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.81