Feasibility of Atezolizumab in Combination With Chemotherapy for Children With Relapsed or Refractory Solid Tumors

Atezolizumab combined with vincristine, irinotecan, and temozolomide was feasible and well tolerated in children with solid tumors. Efficacy of this regimen is now being assessed in relapsed and refractory rhabdomyosarcoma in an ongoing Phase II cohort.

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Institutions

Publication Details

Journal
Pediatric Blood & Cancer
Published
2025-09-12
DOI
https://doi.org/10.1002/pbc.32046
Citations
1
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
1.05

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article

Feasibility of Atezolizumab in Combination With Chemotherapy for Children With Relapsed or Refractory Solid Tumors

Elizabeth Sokol, Shoba A. Navai, Brian Turpin, Dinesh Rakheja et al.
1 citations
Pediatric Blood & Cancer
Cancer Immunotherapy and Biomarkers
1.05
article

Feasibility of Atezolizumab in Combination With Chemotherapy for Children With Relapsed or Refractory Solid Tumors

Elizabeth Sokol, Shoba A. Navai, Brian Turpin, Dinesh Rakheja, Arhanti Sadanand, Kenneth Chen, Sharon Primeaux, Natalie B. Collins, Andrew Y. Koh, David E. Gerber, Avanthi Tayi Shah, Katie M Albert, Theodore Willis Laetsch, Sonja E. Stutzman, MinJae Lee, Matthew Campbell, Deseray Sida
article en
1 citations

Abstract

Atezolizumab combined with vincristine, irinotecan, and temozolomide was feasible and well tolerated in children with solid tumors. Efficacy of this regimen is now being assessed in relapsed and refractory rhabdomyosarcoma in an ongoing Phase II cohort.

Pediatric Blood & CancerVol. 72(12)
Cincinnati Children's Hospital Medical Center (US), Children's Hospital of Philadelphia (US), Baylor College of Medicine (US), University of Washington (US), Lurie Children's Hospital (US), Texas Children's Hospital (US), Children's Cancer Center (US), Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US), The University of Texas Southwestern Medical Center (US)
Alex's Lemonade Stand Foundation for Childhood Cancer, Genentech
Openalex Percentile: Top 18%
Cancer Immunotherapy and Biomarkers
1.05
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