Persistent Off‐Season Dysregulation of Memory B Cell Subsets in Allergic Rhinitis
Even outside allergen exposure, AR patients exhibit systemic B cell dysregulation, characterized by skewed class switching, altered subset distribution, and reduced activation markers expression. These findings underscore persistent immune imbalance in AR, identify potential off-season biomarkers of allergic inflammation.
Authors
- Maryam Jafari (ORCID: https://orcid.org/0000-0002-7261-2191)
- Laila Hellkvist
- Agnetha Karlsson
- Eric Hjalmarsson (ORCID: https://orcid.org/0009-0007-7228-6131)
- Lars‐Olaf Cardell (ORCID: https://orcid.org/0000-0003-0538-9580)
- Susanna Kumlien Georén (ORCID: https://orcid.org/0000-0001-7292-9255)
- Eirini Paziou
Institutions
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
Publication Details
- Journal
- Clinical and Translational Allergy
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/clt2.70100
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.00