All- <i>trans</i> retinoic acid ameliorates S100-induced experimental autoimmune hepatitis by regulating the Treg/Th17 balance
Our findings suggest that atRA ameliorated S100-induced EAH likely by suppressing the IL-6/STAT3 signaling pathway to restore the Treg/Th17 balance. Therefore, atRA may be a promising therapeutic drug for treating AIH.
Authors
- Xun Li (ORCID: https://orcid.org/0009-0006-2744-6514)
- H. Zhao (ORCID: https://orcid.org/0000-0001-9160-8617)
- Yang Luo
- Qiang Li
- Xiaofeng Wei
Institutions
- United States Government Accountability Office (US)
- Second Military Medical University (CN)
- Institute for Regenerative Medicine & Biotherapy (FR)
- Institute of Clinical Research (US)
- Gansu Institute of Political Science and Law (CN)
- The People's Hospital of LinXia (CN)
- Regenerative Medicine Institute (MX)
- Eastern Hepatobiliary Surgery Hospital (CN)
- The First People's Hospital of Jiangxia District (CN)
- First Hospital of Lanzhou University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1080/08923973.2025.2554663
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00