Real‐World Data on Inotuzumab Ozogamicin for Adult Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia: A GRELAL‐Chile Study
InO demonstrated high remission and MRD negativity rates in Chilean patients with R/R ALL, with OS and PFS comparable to existing research. Although SOS incidence was higher, it was generally mild. Achieving MRD negativity and proceeding to Allo-HSCT provided the greatest survival benefit. Study limitations include short follow-up and limited data.
Authors
- Javier Vidal Valenzuela (ORCID: https://orcid.org/0009-0007-3101-9846)
- Jorge Rojas‐Vallejos (ORCID: https://orcid.org/0000-0002-5939-3035)
- Marcelo A. Navarrete (ORCID: https://orcid.org/0000-0002-2044-9548)
- Yorman Flores (ORCID: https://orcid.org/0009-0001-9920-9861)
- Gonzalo Guerrero
- Joaquín Jerez (ORCID: https://orcid.org/0000-0003-3919-6672)
- Francisco Samaniego
- Marcela Espinoza (ORCID: https://orcid.org/0000-0001-9291-646X)
- Natalia Aranguiz
- Guillermo Conte (ORCID: https://orcid.org/0000-0002-0776-7402)
- Nicolás Rodríguez (ORCID: https://orcid.org/0009-0000-3186-6403)
- Mauricio Chandía (ORCID: https://orcid.org/0009-0005-7047-4994)
- Lucas Carcamo
- Eva Zapata (ORCID: https://orcid.org/0000-0002-5027-8508)
- Constanza Flores
- Miguel López
- Ximena Huerta
- Nicolás Quinteros (ORCID: https://orcid.org/0009-0006-2075-8910)
- Daniel Astete
- Agatha Larrazabal
Institutions
- Universidad Andrés Bello (CL)
- Pontificia Universidad Católica de Chile (CL)
- University of Concepción (CL)
- Universidad de Los Andes, Chile (CL)
- Clínica Alemana (CL)
- Hospital Barros Luco-Trudeau (CL)
- Hospital Carlos Van Buren (CL)
- Hospital Regional de Concepción (CL)
- Hospital San Juan de Dios (CL)
- Hospital la Serena (CL)
- Hospital Clínico de la Universidad de Chile (CL)
- Fundación Arturo López Pérez (CL)
- Hospital Dr. Gustavo Fricke (CL)
- Clínica Dávila (CL)
- Hospital San Borja Arriarán (CL)
- Universidad de Magallanes (CL)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/cam4.71230
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00