Biological Plausibility of Using Plasma Amino Acid Profile Determination as a Potential Biomarker for Pediatric Patients with Mild Traumatic Brain Injuries
These patterns represent continuous neurochemical processes involving excitotoxicity and glial regulation, suggesting potential utility as biomarkers for mTBI diagnosis and monitoring. While further validation using larger cohorts is needed, these findings provide compelling evidence of the efficacy of using amino acid profiles to track pediatric mTBI progression and recovery.
Authors
- Fernando Narváez-González (ORCID: https://orcid.org/0000-0001-7229-4675)
- Valentina Vega-Rangel
- Marina Martínez-Vargas (ORCID: https://orcid.org/0000-0002-3729-2161)
- Luis Tristán‐López (ORCID: https://orcid.org/0000-0002-8033-0629)
- Adán Pérez-Arredondo (ORCID: https://orcid.org/0000-0002-0479-6734)
- Camilo Rı́os (ORCID: https://orcid.org/0000-0002-3216-0119)
- Liliana Carmona‐Aparicio (ORCID: https://orcid.org/0000-0001-8721-9387)
- Luz Navarro (ORCID: https://orcid.org/0000-0002-5519-0871)
- Diana Leticia Pérez-Lozano (ORCID: https://orcid.org/0000-0001-6400-0016)
- Eduardo Cázarez-Ramírez (ORCID: https://orcid.org/0000-0002-0918-3910)
- Carlos Jiménez-Gutiérrez (ORCID: https://orcid.org/0000-0003-1108-2139)
- Ivette A. Martínez-Hernández
Institutions
- Hospital General Dr. Manuel Gea Gonzalez (MX)
- Instituto Nacional de Rehabilitación (MX)
- Sociedad Andaluza de Medicina Familiar y Comunitaria (ES)
- Instituto Nacional de Pediatria (MX)
- Instituto Nacional de Neurología y Neurocirugía (MX)
- Universidad del Valle de México (MX)
- Institute for Social Security and Services for State Workers (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Neurology International
- Published
- 2025-09-09
- DOI
- https://doi.org/10.3390/neurolint17090145
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00