Melanin@PLGA/Nuciferine Nanoparticles for Enhanced Photothermal Therapy of Hepatocellular Carcinoma by Promoting Autophagy
MPN enhanced the T1-weighted MRI signal for accurate tumor localization and demonstrated superior photothermal properties. Moreover, MPN potentiated PTT by inducing autophagy overactivation in HCC cells, thereby enhancing ablation efficacy and inhibiting post-PTT tumor growth.
Authors
- Yingxuan Mao
- Mingwei Zhu (ORCID: https://orcid.org/0000-0002-7376-6993)
- Tianxiu Dong
- Jiamei Niu
- Mingming Li (ORCID: https://orcid.org/0000-0003-0621-6227)
- Weidong Wang (ORCID: https://orcid.org/0000-0002-3550-0625)
- Jian Jiang (ORCID: https://orcid.org/0000-0003-2389-4433)
- Xinling Du
- Xiuhua Yang (ORCID: https://orcid.org/0000-0002-4546-8243)
- Linlin Han
Institutions
- Harbin Medical University (CN)
- Heilongjiang University of Chinese Medicine (CN)
- First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/ijn.s536620
- Citations
- 2
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.71