NCCN Guidelines® Insights: Non–Small Cell Lung Cancer, Version 7.2025
The NCCN Guidelines for Non-Small Cell Lung Cancer (NSCLC) provide recommendations for the treatment of NSCLC. These NCCN Guidelines Insights discuss recent updates to the NCCN Guidelines, with a focus on systemic therapy options for the treatment of patients with nonmetastatic NSCLC and the corresponding molecular testing considerations.
Authors
- Jane Yanagawa
- Dawn Owen (ORCID: https://orcid.org/0000-0002-0538-3202)
- Jules Lin (ORCID: https://orcid.org/0000-0003-4733-0659)
- Thomas Ng
- Joe Y. Chang (ORCID: https://orcid.org/0000-0002-8435-2083)
- Andrea L. Axtell (ORCID: https://orcid.org/0000-0003-0916-3327)
- Billy W. Loo (ORCID: https://orcid.org/0000-0002-2521-0544)
- Jessica R. Bauman (ORCID: https://orcid.org/0000-0001-8691-0387)
- Rudy P. Lackner
- Tawee Tanvetyanon (ORCID: https://orcid.org/0000-0002-1287-1757)
- Tejas Patil (ORCID: https://orcid.org/0000-0003-4389-1010)
- Fabien Maldonado (ORCID: https://orcid.org/0000-0002-6504-2063)
- Ankit Bharat (ORCID: https://orcid.org/0000-0002-1248-0457)
- Daniel Morgensztern (ORCID: https://orcid.org/0000-0003-4349-2028)
- Ana Lucia Ruano Mendez
- Patricio Marcelo Polanco (ORCID: https://orcid.org/0000-0002-1719-1208)
- Travis E. Grotz (ORCID: https://orcid.org/0000-0002-7753-097X)
- Trey C. Mullikin (ORCID: https://orcid.org/0000-0002-1099-1763)
- Douglas E. Wood (ORCID: https://orcid.org/0000-0002-1396-7005)
- Dara L. Aisner (ORCID: https://orcid.org/0000-0001-5203-5932)
- Matthew A. Gubens (ORCID: https://orcid.org/0000-0002-6482-1954)
- Gregory J. Riely (ORCID: https://orcid.org/0000-0001-5357-4313)
- Lisa Hang
- Michael Lanuti (ORCID: https://orcid.org/0000-0001-6049-1276)
- Alda L. Tam (ORCID: https://orcid.org/0000-0002-6065-1556)
- Sandip Pravin Patel (ORCID: https://orcid.org/0000-0002-8387-4840)
- Scott Gettinger (ORCID: https://orcid.org/0000-0003-0886-6880)
- Christine M. Lovly (ORCID: https://orcid.org/0000-0002-3641-6361)
- Edwin H. Yau (ORCID: https://orcid.org/0000-0002-3972-0756)
- Theresa A. Shapiro (ORCID: https://orcid.org/0000-0002-6823-7536)
- Aakash Desai (ORCID: https://orcid.org/0000-0002-2943-3817)
- Jonathan Wesley Riess (ORCID: https://orcid.org/0000-0001-7370-7304)
- Thomas J. Dilling (ORCID: https://orcid.org/0000-0003-0257-6989)
- Dwight Hall Owen (ORCID: https://orcid.org/0000-0002-6598-4886)
- Jonathan E. Dowell (ORCID: https://orcid.org/0000-0002-0202-9697)
- Aditi P. Singh (ORCID: https://orcid.org/0000-0002-2063-6407)
- Gregory A. Durm
- Benjamin Levy
- Kristina M. Gregory
- James P. Stevenson
- Aditya Juloori (ORCID: https://orcid.org/0000-0002-7486-6208)
Institutions
- Fox Chase Cancer Center (US)
- Roswell Park Comprehensive Cancer Center (US)
- Barnes-Jewish Hospital (US)
- Cleveland Clinic (US)
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Tennessee Health Science Center (US)
- Breast Cancer Research Foundation (US)
- University of Utah (US)
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- UC San Diego Health System (US)
- Huntsman Cancer Institute (US)
- Cancer Institute (WIA) (IN)
- Susan Thompson Buffett Foundation (US)
- WinnMed (US)
- Yale Cancer Center (US)
- Moffitt Cancer Center (US)
- Massachusetts General Hospital (US)
- Fred Hutch Cancer Center (US)
- Southwestern Medical Center (US)
- Jewish Hospital (US)
- University of Wisconsin Carbone Cancer Center (US)
- Sidney Kimmel Cancer Center (US)
- University Hospitals Seidman Cancer Center (US)
- Duke Medical Center (US)
- University of Colorado Cancer Center (US)
- Smilow Cancer Hospital (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center
- Moores Cancer Center
- University of Chicago Medicine Comprehensive Cancer Center
- UCLA Jonsson Comprehensive Cancer Center
- Vanderbilt-Ingram Cancer Center
- Stanford Cancer Institute
- Duke Cancer Institute
- Fred and Pamela Buffett Cancer Center
- UC Davis Comprehensive Cancer Center
- Harold C. Simmons Comprehensive Cancer Center
- O'Neal Comprehensive Cancer Center
- National Comprehensive Cancer Network
- Indiana University (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
- The University of Texas Southwestern Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of the National Comprehensive Cancer Network
- Published
- 2025-09-01
- DOI
- https://doi.org/10.6004/jnccn.2025.0043
- Citations
- 21
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 31.89