Bioinformatics Analysis and Experimental Validation of Lactylation Related Genes in Lung Adenocarcinoma
LUAD tissues exhibit elevated lactylation levels, suggesting their potential as prognostic biomarkers. The identified genes-KIF2C, MKI67, HMGA1, PFKP, and CCNA2-are highly expressed in cancerous tissues and correlate with LUAD prognosis. These findings highlight their value as tumor biomarkers and therapeutic targets, offering new opportunities for targeted LUAD treatments.
Authors
- Xin Xie
- Fengrui Wu (ORCID: https://orcid.org/0000-0002-6130-1611)
- Bin Liu (ORCID: https://orcid.org/0000-0003-1691-8126)
- Li Gao (ORCID: https://orcid.org/0000-0003-4418-0528)
- Y-C. Zhang
Institutions
- Fuyang Normal University (CN)
- Fuyang City People's Hospital (CN)
- Fuyang Maternity and Child Health Care Hospital (CN)
- Fuyang Second People's Hospital (CN)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/cmar.s533289
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81