Soft-Tissue Congenital Hemangiomas and Related Complications: A Retrospective Cohort of 14 Cases With Emphasis on Prenatal Diagnosis, Counseling, and Postnatal Management

Objectives: We aimed to describe prenatal imaging findings of superficial congenital hemangiomas (CH), review associated complications, and describe outcomes. Methods: A single-center retrospective cohort study spanning 18 years (2006–2024) reviewed imaging and medical charts of fetuses with soft-tissue masses suggestive of CH on prenatal ultrasound and/or magnetic resonance imaging, confirmed postnatally through evolution or histopathology. Results: All 14 cases (7 [50%] head and neck, 5 [36%] extremities, and 2 [14%] trunk) showed hypoechoic hypervascular masses on Doppler ultrasound with internal vascular ectasias, 12 (86%) being well circumscribed, and 5 (36%) having intralesional echogenic foci. Seven (50%) had a large draining vein and 5 (36%) showed right atrial enlargement. Magnetic resonance imaging (n = 11) demonstrated a well-circumscribed lesion in 9 (82%) cases, hypointense in 4 (36%), and iso- to hyperintense in 7 (64%) on T2-weighted imaging. Seven (64%) cases had internal T2-hypointense areas; none showed cystic areas or muscle invasion. One pregnancy was terminated. Of the 13 live births, all lesions showed complete or partial involution within a year; 3 (25%) developed superficial ulceration and 1 (8%) transient symptomatic heart failure. Four patients underwent elective surgery. Conclusion: Fetuses with CH had favorable outcomes, highlighting the importance of accurate prenatal diagnosis and delivery in specialized centers to manage potential complications.

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Publication Details

Journal
Journal of Vascular Anomalies
Published
2025-09-01
DOI
https://doi.org/10.1097/jova.0000000000000117
Primary Topic
Vascular Malformations and Hemangiomas
Type
article
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article

Soft-Tissue Congenital Hemangiomas and Related Complications: A Retrospective Cohort of 14 Cases With Emphasis on Prenatal Diagnosis, Counseling, and Postnatal Management

V. Soupre, Fanny Sauvestre, Antoine Fraissenon, Laurent Guibaud et al.
Journal of Vascular Anomalies
Vascular Malformations and Hemangiomas
article

Soft-Tissue Congenital Hemangiomas and Related Complications: A Retrospective Cohort of 14 Cases With Emphasis on Prenatal Diagnosis, Counseling, and Postnatal Management

V. Soupre, Fanny Sauvestre, Antoine Fraissenon, Laurent Guibaud, Mathilde Ferry, Sara Cabet, Claire Combescure, Francis Fortin, M. Bigorre, An Lesage
article en

Abstract

Objectives: We aimed to describe prenatal imaging findings of superficial congenital hemangiomas (CH), review associated complications, and describe outcomes. Methods: A single-center retrospective cohort study spanning 18 years (2006–2024) reviewed imaging and medical charts of fetuses with soft-tissue masses suggestive of CH on prenatal ultrasound and/or magnetic resonance imaging, confirmed postnatally through evolution or histopathology. Results: All 14 cases (7 [50%] head and neck, 5 [36%] extremities, and 2 [14%] trunk) showed hypoechoic hypervascular masses on Doppler ultrasound with internal vascular ectasias, 12 (86%) being well circumscribed, and 5 (36%) having intralesional echogenic foci. Seven (50%) had a large draining vein and 5 (36%) showed right atrial enlargement. Magnetic resonance imaging (n = 11) demonstrated a well-circumscribed lesion in 9 (82%) cases, hypointense in 4 (36%), and iso- to hyperintense in 7 (64%) on T2-weighted imaging. Seven (64%) cases had internal T2-hypointense areas; none showed cystic areas or muscle invasion. One pregnancy was terminated. Of the 13 live births, all lesions showed complete or partial involution within a year; 3 (25%) developed superficial ulceration and 1 (8%) transient symptomatic heart failure. Four patients underwent elective surgery. Conclusion: Fetuses with CH had favorable outcomes, highlighting the importance of accurate prenatal diagnosis and delivery in specialized centers to manage potential complications.

Journal of Vascular AnomaliesVol. 6(3)
Université Claude Bernard Lyon 1 (FR), Hôpital Necker-Enfants Malades (FR), Centre Hospitalier Universitaire Sainte-Justine (CA), Centre Hospitalier Universitaire de Bordeaux (FR), Hôpital Femme Mère Enfant (FR), Centre Hospitalier de Saint-Brieuc (FR), Saint Laurent Polyclinique (FR), Hôpital Nord (FR), Imagerie Médicale et Radiothérapie Drôme Ardèche (FR), Hôpital Mère-Enfant (FR)
Openalex Percentile: Top 61%
Vascular Malformations and Hemangiomas
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