Cetirizine Consumption: When an Antihistamine Sparks an Unexpected Medical Twist in a Toddler – A Case Report of Somnolence and Bradycardia

We report the case of a 2-year-old boy who ingested approximately half a bottle of cetirizine syrup (~15 mg total).Within one hour, the child developed notable somnolence and bradycardia (heart rate ~60-76 bpm), though respiratory function and capillary refill time remained stable.He was managed with supportive care and admitted for close observation.Over a six-hour period, the somnolence and bradycardia gradually resolved without intervention.The child was discharged after 13 hours of monitoring in stable condition, having returned to baseline neurological and cardiovascular function.Although cetirizine has a wide therapeutic index, this case highlights that overdose in young children can cause transient cardiovascular and CNS effects.Timely recognition, conservative management, and observation are usually sufficient for complete recovery.Cetirizine poisoning in children is generally self-limiting, but may present with somnolence and bradycardia.Prompt observation and supportive care lead to favorable outcomes.

Publication Details

Journal
Acta Scientific Paediatrics
Published
2025-09-01
DOI
https://doi.org/10.31080/aspe.2025.08.0749
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
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article

Cetirizine Consumption: When an Antihistamine Sparks an Unexpected Medical Twist in a Toddler – A Case Report of Somnolence and Bradycardia

Acta Scientific Paediatrics
Drug-Induced Adverse Reactions
article

Cetirizine Consumption: When an Antihistamine Sparks an Unexpected Medical Twist in a Toddler – A Case Report of Somnolence and Bradycardia

article en

Abstract

We report the case of a 2-year-old boy who ingested approximately half a bottle of cetirizine syrup (~15 mg total).Within one hour, the child developed notable somnolence and bradycardia (heart rate ~60-76 bpm), though respiratory function and capillary refill time remained stable.He was managed with supportive care and admitted for close observation.Over a six-hour period, the somnolence and bradycardia gradually resolved without intervention.The child was discharged after 13 hours of monitoring in stable condition, having returned to baseline neurological and cardiovascular function.Although cetirizine has a wide therapeutic index, this case highlights that overdose in young children can cause transient cardiovascular and CNS effects.Timely recognition, conservative management, and observation are usually sufficient for complete recovery.Cetirizine poisoning in children is generally self-limiting, but may present with somnolence and bradycardia.Prompt observation and supportive care lead to favorable outcomes.

Acta Scientific Paediatrics
Openalex Percentile: Top 73%
Drug-Induced Adverse Reactions
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