MAIT Cells with High PFN1 Expression Mediate Immune Activation and Metabolic Reprogramming in Psoriasis
Our integrative analysis highlights MAIT cells and PFN1 as likely contributors to psoriasis pathogenesis. These findings offer insights into immune and metabolic alterations, suggesting potential targets for therapeutic intervention.
Authors
- Man-Ning Wu (ORCID: https://orcid.org/0000-0002-2154-1258)
- Yue-Min Zou
- Sung Pil Hong (ORCID: https://orcid.org/0000-0001-8485-6348)
- Yanping Bai (ORCID: https://orcid.org/0000-0003-3365-4409)
- Xiangnan Zhou (ORCID: https://orcid.org/0000-0002-6715-5176)
- Lei Wang (ORCID: https://orcid.org/0000-0003-0734-7026)
Institutions
- Beijing University of Chinese Medicine (CN)
- China-Japan Friendship Hospital (CN)
Publication Details
- Journal
- Clinical Cosmetic and Investigational Dermatology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/ccid.s535795
- Citations
- 1
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Natural Science Foundation of China
- State Administration of Traditional Chinese Medicine of the People's Republic of China