Huashi Baidu granules alleviates LPS-induced acute lung injury by targeting TACE-mediated inflammatory signaling and stress granules disassembly
HBG, with licorice as its pivotal herb, mitigates ALI by targeting TACE-mediated inflammatory cascades and modulating SGs. The licorice-derived licochalcone B exerts a pivotal effect in this mechanism, offering insights for optimizing traditional formulations and developing novel therapies.
Authors
- Jing Gong
- Jun Huang (ORCID: https://orcid.org/0000-0003-0271-4384)
- Jingjing Zhang (ORCID: https://orcid.org/0000-0002-5496-4986)
- Yanan Sun (ORCID: https://orcid.org/0000-0002-8363-6957)
- Yuan Ma (ORCID: https://orcid.org/0000-0001-8004-2793)
- Wenyu Yang (ORCID: https://orcid.org/0000-0002-4882-2607)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2025-09-08
- DOI
- https://doi.org/10.1016/j.jep.2025.120580
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00