EMX2OS serves as a biomarker of neonatal sepsis and participates acute lung injury through enhancing ferroptosis
This study reveals for the first time that EMX2OS serves as a diagnostic marker for NS and promotes ferroptosis through miR-654-3p/AKT3 axis, thereby exacerbating lung injury. EMX2OS to regulate ferroptosis may become potential therapeutic strategies for lung injury.
Authors
- Xuexiang Li (ORCID: https://orcid.org/0000-0002-9309-8259)
- Lili Shi (ORCID: https://orcid.org/0000-0001-9629-0513)
- Guang Shan (ORCID: https://orcid.org/0000-0001-9133-6500)
- Zhihua Liu (ORCID: https://orcid.org/0000-0001-5784-9724)
- Zhiqiang Liu (ORCID: https://orcid.org/0000-0003-3821-0321)
Institutions
- Shengli Oilfield Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-09-09
- DOI
- https://doi.org/10.3389/fped.2025.1654832
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00