Monomelic, Multicentric, Metachronous Primary Chondrosarcoma of the Lower Limb: A Case Report

An elderly man presented with a two-month history of swelling in the left lower leg. He had a prior history of chondrosarcoma of the first metatarsal, for which he underwent resection of the metatarsal and great toe in 2018. Current radiographs revealed an aggressive lytic lesion with mild sclerosis and cortical breach involving the medial tibial condyle. MRI demonstrated a heterogeneous lesion in the proximal tibia with multifocal cortical breaches and adjacent soft tissue involvement. Histopathological examination confirmed a diagnosis of low-grade chondrosarcoma. The patient subsequently underwent extended resection with endoprosthetic reconstruction.

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Journal
Cureus
Published
2025-09-08
DOI
https://doi.org/10.7759/cureus.91869
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Monomelic, Multicentric, Metachronous Primary Chondrosarcoma of the Lower Limb: A Case Report

Prabodh Kantiwal, Siddhi Chawla, Divya Aggarwal
Cureus
Bone Tumor Diagnosis and Treatments
article

Monomelic, Multicentric, Metachronous Primary Chondrosarcoma of the Lower Limb: A Case Report

Prabodh Kantiwal, Siddhi Chawla, Divya Aggarwal
article en

Abstract

An elderly man presented with a two-month history of swelling in the left lower leg. He had a prior history of chondrosarcoma of the first metatarsal, for which he underwent resection of the metatarsal and great toe in 2018. Current radiographs revealed an aggressive lytic lesion with mild sclerosis and cortical breach involving the medial tibial condyle. MRI demonstrated a heterogeneous lesion in the proximal tibia with multifocal cortical breaches and adjacent soft tissue involvement. Histopathological examination confirmed a diagnosis of low-grade chondrosarcoma. The patient subsequently underwent extended resection with endoprosthetic reconstruction.

CureusVol. 17(9)
All India Institute of Medical Sciences Jodhpur (IN)
Openalex Percentile: Top 64%
Bone Tumor Diagnosis and Treatments
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