Alveolar-derived autologous blood clot as a scaffold for regenerative endodontic treatment: An observational study

Regenerative endodontic treatment (RET) has transformed the management of immature necrotic permanent teeth by promoting biological healing and root development. Hence, a total of 20 patients aged 8-16 years with necrotic immature anterior teeth were enrolled. Blood was collected from a fresh alveolar socket and introduced into the canal space following canal disinfection with triple antibiotic paste. 83.3% showed complete periapical healing, while 72.2% exhibited apical closure and root lengthening by 12 months. We further found that clinical signs such as pain, swelling and sinus tract were resolved in all cases.