Effect of healthy lifestyle on renal dysfunction risk: interactions with genetic risk

Maintaining a healthy lifestyle is associated with lower risk of renal dysfunction, regardless of genetic risk. Combining PRSs with lifestyle information may enhance risk stratification, although further studies are needed to improve predictive accuracy.

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Publication Details

Journal
Clinical Kidney Journal
Published
2025-09-09
DOI
https://doi.org/10.1093/ckj/sfaf275
Primary Topic
Birth, Development, and Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Effect of healthy lifestyle on renal dysfunction risk: interactions with genetic risk

Taku Obara, Nobuo Fuse, Tomoko Kobayashi, Satoshi Nagaie et al.
Clinical Kidney Journal
Birth, Development, and Health
article

Effect of healthy lifestyle on renal dysfunction risk: interactions with genetic risk

Taku Obara, Nobuo Fuse, Tomoko Kobayashi, Satoshi Nagaie, Sayuri Tokioka, Rieko Hatanaka, Junichi Sugawara, Akira Narita, Atsushi Hozawa, Eiichi N. Kodama, Kengo Kinoshita, Takumi Hirata, Masato Takase, Yohei Hamanaka, Kotaro Nochioka, Naoki Nakaya, Soichi Ogishima, Ippei Takahashi, Mana Kogure, Ikumi Kanno, Hisashi Ohseto, Koichi Matsuda, Gen Tamiya, Kumi Nakaya, Ippei Chiba, Mami Ishikuro, Masatsugu Orui, Akira Uruno, Shinichi Kuriyama, Tomohiro Nakamura, Yoko Izumi, Masayuki Yamamoto, Naho Tsuchiya
article en

Abstract

Maintaining a healthy lifestyle is associated with lower risk of renal dysfunction, regardless of genetic risk. Combining PRSs with lifestyle information may enhance risk stratification, although further studies are needed to improve predictive accuracy.

Clinical Kidney JournalVol. 18(10)
Suzuki (Japan) (JP), Tohoku University (JP), Kyoto Women's University (JP), Tohoku University Hospital (JP), RIKEN Center for Advanced Intelligence Project (JP), Tohoku Medical Megabank Organization (JP), Tokyo Metropolitan Institute of Gerontology (JP), The University of Tokyo (JP)
Japan Agency for Medical Research and Development, Ministry of Education, Culture, Sports, Science and Technology, Japan Society for the Promotion of Science
Openalex Percentile: Top 66%
Birth, Development, and Health
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