Bosentan Delivery via Nano Metal-Organic Framework nanoMIL-89 Restores Vascular Homeostasis in Pulmonary Arterial Hypertension
These findings highlight Bosentan@nanoMIL-89 as a promising nanotherapeutic platform for PAH. By improving efficacy while mitigating systemic side effects, this approach reinforces the broader potential of MOF-based drug delivery systems in the management of vascular diseases.
Authors
- Mohammad Ahmad Al-Ghouti (ORCID: https://orcid.org/0000-0002-9943-1091)
- Nura A. Mohamed
- Ayman Al Haj Zen (ORCID: https://orcid.org/0000-0002-2145-2925)
- Richa Gill (ORCID: https://orcid.org/0000-0003-2239-551X)
- Hend Salah Fayed (ORCID: https://orcid.org/0000-0002-0753-9944)
- Hanan Abunada (ORCID: https://orcid.org/0000-0003-2186-2518)
- Mashael Al‐Badr
- Haissam Abou-Saleh (ORCID: https://orcid.org/0000-0003-3460-1413)
- Md. Tanvir Rahman (ORCID: https://orcid.org/0000-0001-5432-480X)
Institutions
- Hamad bin Khalifa University (QA)
- Qatar University (QA)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/ijn.s535437
- Citations
- 1
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.52