Unique Presentation of Postpartum Hypereosinophilic Syndrome With Atypical Features and Therapeutic Challenges

The patient described in this case met diagnostic criteria for HES; however, the complicated clinical and laboratory features made it challenging to characterize her disease as a specific HES variant, rendering it difficult to determine the optimal treatment regimen. Further therapy was complicated by a new pregnancy. It is important for clinicians to recognize an abnormally elevated AEC, promptly initiate systematic evaluation, and minimize delays in diagnosis and treatment of potential HES in order to avoid the extensive morbidity and mortality that can be associated with HES.