Assessment of the Potential Risk of Cytochrome P450-Mediated Drug–Drug Interactions in Psychiatric Inpatients

Polypharmacy increases the risk of drug–drug interactions (DDIs) among patients with psychiatric disorders. Several psychiatric medications act as substrates, inhibitors, or inducers of cytochrome P450 (CYP), necessitating careful evaluation of CYP-mediated DDIs before administration. This study aimed to evaluate the potential risk of CYP-mediated DDIs among psychiatric inpatients.

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Publication Details

Journal
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)
Published
2025-09-09
DOI
https://doi.org/10.5649/jjphcs.51.509
Primary Topic
Pharmaceutical Practices and Patient Outcomes
Type
article
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article

Assessment of the Potential Risk of Cytochrome P450-Mediated Drug–Drug Interactions in Psychiatric Inpatients

Kiyoto Kasai, Tappei Takada, Kayo Ichihashi, Yoshiyuki Ohno et al.
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)
Pharmaceutical Practices and Patient Outcomes
article

Assessment of the Potential Risk of Cytochrome P450-Mediated Drug–Drug Interactions in Psychiatric Inpatients

Kiyoto Kasai, Tappei Takada, Kayo Ichihashi, Yoshiyuki Ohno, Toyohito Oriyama, Kota Imai
article en

Abstract

Polypharmacy increases the risk of drug–drug interactions (DDIs) among patients with psychiatric disorders. Several psychiatric medications act as substrates, inhibitors, or inducers of cytochrome P450 (CYP), necessitating careful evaluation of CYP-mediated DDIs before administration. This study aimed to evaluate the potential risk of CYP-mediated DDIs among psychiatric inpatients.

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)Vol. 51(9)
University of Tokyo Hospital (JP)
Openalex Percentile: Top 71%
Pharmaceutical Practices and Patient Outcomes
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