Ectopic HLA-II Expression in ESCC: Exploration of Its Relationship with Neoantigen Burden and Patient Survival
Ectopic HLA-II expression in ESCC may influence the tumor immune microenvironment, while the prognostic value of MHC-II-restricted neoantigen burden in ESCC remains unclear, providing potential implications for immunotherapy strategies.
Authors
- Zhenguo Cheng (ORCID: https://orcid.org/0000-0001-6375-3438)
- Nicholas R. Lemoine (ORCID: https://orcid.org/0000-0001-8675-058X)
- Yupei Ji (ORCID: https://orcid.org/0009-0000-8655-5645)
- Louisa S. Chard (ORCID: https://orcid.org/0000-0003-2380-0900)
- Shuangshuang Lu (ORCID: https://orcid.org/0000-0002-8144-1830)
- Yaohe Wang (ORCID: https://orcid.org/0000-0003-2367-6313)
- Renato B. Baleeiro (ORCID: https://orcid.org/0000-0001-7568-7570)
- Zhizhong Wang (ORCID: https://orcid.org/0000-0002-7505-7840)
Institutions
- Queen Mary University of London (GB)
- Zhengzhou University (CN)
- Henan Cancer Hospital (CN)
Publication Details
- Journal
- Cells
- Published
- 2025-09-08
- DOI
- https://doi.org/10.3390/cells14171403
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cancer Research UK
- Medical Research Council