Comparative outcomes of culprit-only versus complete revascularisation in cardiogenic shock complicating acute myocardial infarction: insights from the Gulf-Cardiogenic Shock registry

No statistically significant differences in hospital mortality or long-term MACCE-free survival were observed between culprit-only PCI and multivessel PCI strategies in patients with cardiogenic shock complicating acute myocardial infarction. However, patients older than 70 years may benefit from a multivessel PCI approach. These findings support current guideline recommendations favouring culprit-only PCI due to reduced procedural complexity while highlighting the need for individualised treatment strategies based on patient age and clinical factors. Further prospective randomised studies are needed to validate these age-specific findings and identify optimal patient selection criteria for each revascularisation strategy.

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Publication Details

Journal
BMJ Open
Published
2025-09-01
DOI
https://doi.org/10.1136/bmjopen-2025-101843
Primary Topic
Mechanical Circulatory Support Devices
Type
article
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article

Comparative outcomes of culprit-only versus complete revascularisation in cardiogenic shock complicating acute myocardial infarction: insights from the Gulf-Cardiogenic Shock registry

Mohammed Alshehri, Rajesh Rajan, Ahmed Abdullah Jamjoom, Shahrukh Hashmani et al.
BMJ Open
Mechanical Circulatory Support Devices
article

Comparative outcomes of culprit-only versus complete revascularisation in cardiogenic shock complicating acute myocardial infarction: insights from the Gulf-Cardiogenic Shock registry

Mohammed Alshehri, Rajesh Rajan, Ahmed Abdullah Jamjoom, Shahrukh Hashmani, Mohamed Ajaz Ghani, Abdelmaksoud Elganady, Mohammed Qutub, Adnan Fathey Hussien, Youssef Elmahrouk, Prashanth Panduranga, Jassim Al Suwaidi, Mohammed Al‐Jarallah, Amr A. Arafat, Amir Lotfi, Amin Daoulah, Abdullah Alenezi, Ali Alshehri, Hassan Khan, Said Al Maashani, Ahmed A. Ghonim, Seraj Abualnaja, Ahmed F. Elmahrouk, Abeer M Shawky, Wael Almahmeed, Tarique Shahzad Chachar, Ibrahim A. M. Abdulhabeeb, Alaa Aldossari, Bandar Alshehri, Ahmad Hersi, Khalid Z. Alshali, Sultan Alobaikan, Mohammed Balghith, Nooraldaem Yousif, Abdulrahman Almoghairi, Badr Alzahrani, Abdulrahman Arabi, Alsayed Ali Almarghany, Mubarak Aldossari, Khaled Almerri, Waleed Alharbi, Omar Kanbr, Haitham Amin, Abdulrahman Alqahtani, Laura AlObaid, Mohamed N. Alama, Shaber Seraj, Abeer Said Mohamed Al Rawahi, Marwa Abd Elghany Albasiouny Alkholy, Mokhtar Abdirahman Kahin, Ayman Basardah, Awad Al‐Qahtani, Taher Hassan, F. Nasser, Hatem Aloui, Razan waleed W Alsofayan, Mohamed Mohammednabil A Alama, Ayman Al Hussini, Sara Shawki Saati
article en

Abstract

No statistically significant differences in hospital mortality or long-term MACCE-free survival were observed between culprit-only PCI and multivessel PCI strategies in patients with cardiogenic shock complicating acute myocardial infarction. However, patients older than 70 years may benefit from a multivessel PCI approach. These findings support current guideline recommendations favouring culprit-only PCI due to reduced procedural complexity while highlighting the need for individualised treatment strategies based on patient age and clinical factors. Further prospective randomised studies are needed to validate these age-specific findings and identify optimal patient selection criteria for each revascularisation strategy.

BMJ OpenVol. 15(9)
Ministry of Defence (GB), Cleveland Clinic (US), Baystate Medical Center (US), Alfaisal University (SA), Prince Sultan University (SA), Royal College of Surgeons in Ireland (IE), Royal College of Surgeons of England (GB), Al-Azhar University (EG), King Abdulaziz University (SA), King Saud bin Abdulaziz University for Health Sciences (SA), Tanta University (EG), King Faisal Specialist Hospital & Research Centre (SA), King Saud Medical City (SA), Shaikh Khalifa Medical City (AE), King Fahd Medical City (SA), King Saud University (SA), King Abdulaziz Medical City (SA), Amiri Hospital (KW), Royal College of Veterinary Surgeons (GB), King Abdullah International Medical Research Center (SA), Bugshan Hospital (SA), Royal Brompton Hospital (GB), Chest Diseases Hospital (KW), Armed Forces Hospital (SA), Ministry of Health (SA), Royal Hospital (OM), King Abdulaziz Hospital (SA), Sultan Qaboos University Hospital (OM), King Fahad Hospital Jeddah (SA), Islamic University of Madinah (SA), King's College Hospital (GB), Elrazi University, Hamad Medical Corporation (QA), King Khalid University (SA)
Openalex Percentile: Top 77%
Mechanical Circulatory Support Devices
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