Dissecting the Causal Association Between Bulimia Nervosa and Structural Brain Abnormalities: A Two‐Sample Bidirectional Mendelian Randomization Study
Our findings confirmed the potential causal effects of BN on brain structure changes involving multiple functional regions and identified that genetically determined variation in specific brain structural regions could be causal for BN to some extent.
Authors
- Xinghao Wang (ORCID: https://orcid.org/0000-0001-5751-7383)
- Marcin Grzegorzek (ORCID: https://orcid.org/0000-0003-4877-8287)
- Xinyu Huang (ORCID: https://orcid.org/0000-0003-3210-3891)
- Qian Chen (ORCID: https://orcid.org/0000-0001-5210-9647)
- Yiling Wang (ORCID: https://orcid.org/0009-0001-5146-7829)
- Weihua Li (ORCID: https://orcid.org/0000-0003-3216-7385)
- Peng Zhang (ORCID: https://orcid.org/0000-0003-4278-0036)
- Lirong Tang
- J. Wang (ORCID: https://orcid.org/0000-0002-4099-7824)
- Zhenchang Wang (ORCID: https://orcid.org/0000-0002-9551-2660)
Institutions
- Capital Medical University (CN)
- German Research Centre for Artificial Intelligence (DE)
- Beijing Anding Hospital (CN)
- Beijing Friendship Hospital (CN)
- China Medical University (CN)
- University of Lübeck (DE)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/brb3.70859
- Citations
- 1
- Primary Topic
- Eating Disorders and Behaviors
- Type
- article
- Field-Weighted Citation Impact
- 2.31
Funders
- National Natural Science Foundation of China
- Capital Medical University
- China Scholarship Council